Publications (1994-2000)

Fu, H. R. S. Subramanian, and S. C. Masters. 2000. 14-3-3 Proteins: structure, function, and regulation. Annual Review of Pharmacology and Toxicology. 40: 619-649.

Athwal, G.S., Lombardo, C.R., Huber, J.L., Masters, S.C., Fu, H., and Huber , S.C. 2000. Modulation of 14-3-3 interactions with target proteins by physical and metabolic effectors. Plant Cell Physiol . 41:523-33.

Wang, B., H. Yang, Y. Liu, T. Jelinek, L. Zhang, E. Ruoslahti, and H. Fu. 1999. Isolation of high affinity peptide antagonists for 14-3-3 proteins by phage display. Biochemistry. 38:12499-504.

Zhang, L., H. Wang, S. C. Masters, B. Wang, J. T. Barbieri, and H. Fu. 1999. Residues of 14-3-3 z required for activation of exoenzyme S of Pseudomonas aeruginosa . Biochemistry. 38:12159-12164 .

Zhang, L., J. Chen, and H. Fu. 1999. Suppression of apoptosis signal-regulating Kinase1- induced cell death by 14-3-3 proteins. Proc. Natl. Acad. Sci. USA. 96: 8511-8515

Masters, S. C., K. J. Pederson, L. Zhang, J. T. Barbieri, and H. Fu. 1999. Direct interaction of 14-3-3 with a nonphosphorylated protein ligand, exoenzyme S of Pseudomonas aeruginosa . Biochemistry . 38:5216-5221.

Megidish, T., J. Cooper, L. Zhang, H. Fu, and S. Hakomori. 1998. A novel sphingosine- dependent protein kinase (SDK1) is associated with and specifically phosphorylates certain isoforms of 14-3-3 protein . J. Biol. Chem . 273: 21834-21845.

Wang, H., L. Zhang, R. Liddington, and H. Fu. 1998. Mutations in the hydrophobic surface of an amphipathic groove of 14-3-3zeta disrupt its interaction with Raf kinase. J. Biol. Chem. 273: 16297-16304.

Petosa, C., S. C. Masters, L. A. Bankston, J. Pohl, B. Wang, H. Fu, and R. C. Liddington. 1998. 14-3-3zeta binds a serine-phsphorylated Raf peptide and a high-affinity unphosphorylated peptide via its conserved amphipathic groove. J. Biol. Chem 273: 16305-16310.

Datta, S. R., H. Dudek, X. Tao , S. Masters, H. Fu, Y. Gotoh, and M. E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241.

Clark, G. J., J. K. Drugan, K. L. Rossman, , J. W. Carpenter, K. Rogers-Graham, H. Fu, C. J. Der, and S. L. Campbell. 1997. 14-3-3zeta negatively regulates Raf-1 activity by Interactions with the Raf-1 cysteine-rich domain. J. Biol. Chem. 272:20990-20993.

Zhang, L., H. Wang, D. Liu, R. Liddington, and H. Fu. 1997. Raf-1 kinase and ExoS bind to 14-3-3zeta through a common site involving lysine-49. J. Biol. Chem. 272:13717-13724.

Fu, H., S.R. Blanke, L.C. Mattheakis and R.J. Collier. (1997) Selection of diphtheria toxin active-site mutants in yeast: rediscovery of glutamate acid-149 as a key residue . Adv. Exp. Med. Biol . 419 : 45-52.

Liu, D., J. Bienkowska, C. Petosa, R. J. Collier, H. Fu, and R. Liddington. 1995. Crystal structure of the zeta isoform of the 14-3-3 protein. Nature 376:191-194.

Fu, H., K. Xia, D. C. Pallas, C. Cui, K. Conroy, R. P. Narsimhan, H. Mamon, R. J. Collier, and T. M. Roberts. 1994. Interaction of protein kinase Raf-1 with 14-3-3 proteins. Science 266:126-129.

Reuther, G. W., H. Fu, L. D. Cripe, R. J. Collier and A. M. Pendergast. 1994. Association of cBcr and Bcr-Abl with members of the 14-3-3 family of proteins. Science 266:129-133.

Pallas, D., H. Fu, L. Haehnel, W. Weller, R. J. Collier and T. M. Roberts. 1994. Association of polyomavirus middle tumor antigen with 14-3-3 proteins. Science 265:535-537.

Lu, G. H., N. C. de Vetten, T. Isobe, H. Fu, G. P. H. van Heusdon, and R. J. Ferl. 1994. A single Arabidopsis GF14 isoform possesses diverse biochemical characteristics of 14-3-3 homologues. Plant Mol. Biol. 25 : 659-667.

Chen, Z., H. Fu, R. Ferl, P. M. Hasegawa, and R. A. Bressan. 1994. A NaCl-regulated plant gene encoding a 14-3-3 protein that activates ADP-ribosyltransferase and inhibits protein kinase C. Plant J. 6:729-740.

Fu, H., J. Coburn, and R. J. Collier. 1994. Activation of ADP-ribosylating exoenzyme S of Pseudomonas aeruginosa by eukaryotic 14-3-3 proteins, p388-389. In Freer et al. (ed.). Bacterial protein toxins, Zbl. Bakt. Suppl. 24. Gustav Fischer, New York .