Publications (2001-2005)

Coblitz , B , S. Shikano, M. Wu, S. B. Gabelli, L. M. Cockrell, M. Spieker, Y. Hanyu, H. Fu, M. Amzel, M. Li (2005) Carboxyl-terminal recognition by 14-3-3 protein for surface expression of membrane receptors J. Biol. Chem. 280(43):36263-72.

Hu, Y., L. Xia, H. Fu, K. Ye (2005) Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation. EMBO J 24(20):3543-54.

Sun, S. Y., L. M. Rosenberg, X. Wang, Z. Zhou, P. Yue, H. Fu, and F. R. Khuri (2005) Activation of Akt and eIF4E survival pathways by rapamycin-mediated mTOR inhibition. Cancer Res. 65(16):7052-8.

Sun, S.Y., Z. Zhou, R. Wang, H. Fu and F. R. Khuri (2004) The farnesyltransferase inhibitor Lonafarnib induces growth arrest or apoptosis of human lung cancer cells without downregulation of Akt. Cancer Biology & Therapy 3:1092-8.

Ku , Nam -On, H. Fu, and M. Bishr Omary. (2004) Raf-1 activation disrupts its binding to keratins during cell stress. The Journal of Cell Biology 166:479-85.

Goldman, E. H., L. Chen, and H. Fu. (2004) Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at Ser967 and 14-3-3 dissociation. J Biol Chem. 279:10442-10449.

Fujii, K., E. H. Goldman, L. Zhang, J. Chen, and H. Fu. (2004) Negative Control of Apoptosis Signal-regulating Kinase 1 through Phosphorylation of Ser-1034. Oncogene 23:5099-5104.

Subramanian, R. R., H. Zhang, H. Wang, H. Ichijo, T. Miyashita, and H. Fu. (2004) Interaction of Apoptosis Signal-regulating Kinase 1 with isoforms of 14-3-3 Proteins. Exp. Cell Research. 294:581-91.

Chen, J., I. R. Williams, J. Kutok, N. Duclos, E. Anastasiadou, S. C. Masters, H. Fu, and D. G. Gilliland. (2004) Positive and negative roles of the WW-like domain in TEL-PDGF b R transformation in vitro and in vivo. Blood . 104:535-542

Akikazu Hamaguchi, Erika Suzuki, Kimie Murayama, Tsutomu Fujimura, Toshiyuki Hikita, Kazuhisa Iwabuchi, Kazuko Handa, Donald A. Withers, Shane C Masters, Haian Fu, Senitiroh Hakomori. 2003. Sphingosine-dependent protein kinase 1 (SDK1) is identified as the kinase domain of PKC d . J Biol Chem . 2003 Oct 17; 278(42): 41557-65.

Akikazu Hamaguchi, Erika Suzuki, Kimie Murayama, Tsutomu Fujimura, Toshiyuki Hikita, Kazuhisa Iwabuchi, Kazuko Handa, Donald A. Withers, Shane C Masters, Haian Fu, Senitiroh Hakomori. 2003. A sphingosine-dependent protein kinase that specifically phosphorylates 14-3-3 (SDK1) is identified as the kinase domain of PKCd: A preliminary note. Biochem Biophys Res Commun , 307:589-94

Truong, A. B., S. C. Masters, H. Yang, and H. Fu. 2002. Role of the 14-3-3 C-terminal loop in ligand interaction. Proteins: structure, function, and genetics 49:321-325.

Masters, S. C., R. R. Subramanian, A. Truong, H. Yang, K. Fujii, H. Zhang, H. Fu. 2002. Prosurvival function of 14-3-3 proteins. Biochem. Soc. Transactions 30:360-365

Kahn, R. A. H. Fu, and C. R. Roy. 2002. Cellular hijacking: a common strategy for Microbial infection. Trends in Biochemical Sciences . 27:308-314

Masters, S. C. and H. Fu. 2001. 14-3-3 proteins mediate an essential anti-apoptotic signal. J. Biol. Chem . 276:45193-200

Subramanian, R. R., S. C. Masters, H. Zhang, and H. Fu. 2001. Functional conservation of 14-3-3 isoforms in inhibiting Bad-induced apoptosis. Experimental Cell Research 271:142-51

Masters, S.C., H. Yang, S. R. Datta, M. E. Greenberg, H. Fu. 2001. 14-3-3 inhibits Bad induced cell death through serine-136. Mol. Pharm. 60:1325-31

Chen, J., K. Fujii, L. Zhang, T. M. Roberts, and H. Fu. 2001. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 in a MEK-ERK independent mechanism. Proc. Natl. Acad. Sci. USA . 98:7783-8

Yang, H, S. C. Masters, H. Wang, and H. Fu. 2001. The proapoptotic protein Bad binds the amphipathic groove of 14-3-3 z . Biochim. Biophys. Acta .1547:313-9.

Chiang, C., G. Harris, C. Ellig, S. C. Masters, R. Subramanian, S. Shenolikar, B. E.
Wadzinski, and E. Yang. 2001. Protein phosphatase 2A activates the pro-apoptotic function of BAD by a mechanism requiring 14-3-3 dissociation. Blood. 97:1289-97