Michael Iuvone , Ph.D.
     
   
     
      Emory University School of Medicine  
      5107 Rollins Research Center  
      1510 Clifton Road  
      Atlanta, GA 30322-3090  
      Tel: 404-727-5989  
      Tel: 404-727-0358 (Lab)  
      Fax: 404-727-0365  
      miuvone@pharm.emory.edu  
         
      Ph.D., University of Florida, 1976  
      Postdoctoral Fellow, National Institute of Mental Health, 1976-78  
        Emory University, 1978  
        Jointly Professor of Ophthalmology  
    Research Interest:      
   
     
 
Current and General Research Activities: Neurotransmitters, neuromodulators and hormones are three major classes of compounds responsible for intercellular communication in vertebrates. The general research interest of my laboratory is in the molecular, cellular and pharmacological regulation of these compounds. Currently, we are studying the regulation of melatonin and catecholamine systems in retina, brain, and pineal gland. Melatonin is a hormone secreted by the pineal gland and also functions as a retinal neuromodulator, synthesized in photoreceptors. Dopamine functions as both a neurotransmitter and a neuromodulator in retina and brain. In my laboratory, cell culture, tissue culture, and neurochemical methodologies are used to investigate the cellular mechanisms for regulating the synthesis, release and actions of these compounds, with specific interests in receptors, second messengers, and enzyme regulation.