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Choose a year below to view papers published within that
year. *Publications at Emory University
(for additional publications go to People
and look at individual CV's)
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 2008  2007 2006 2005 2004 2003 2001 2000 1999 1998 1997 1995 1994-earlier |
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2008
Publications*
* Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone
KH, McCoy KL, Palmini RB, Junge CE, Lee CJ, Yepes M, Hepler JR,
Traynelis SF (2008) Plasmin potentiates synaptic NMDA receptor function
in hippocmapl neurons through activation of PAR1. J Biol Chem. Epub ahead of print
* Erreger
K, Traynelis SF (2008) Zinc inhibition
of rat NR1/NR2A N-methyl-D-aspartate receptors. J Physiol. 586: 763-778.
* Chen
PE, Geballe MT, Katz E, Erreger K,
Livesey MR,
O'Toole KK, Le P, Lee CJ, Snyder JP, Traynelis SF, Wyllie DJ (2008)
Modulation of glycine potency in rat recombinant NMDA receptors
containing chimeric NR2A/2D subunits expressed in Xenopus laevis
oocytes. J Physiol. 586:
227-245.
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2007
Publications*
* Dravid
SM, Erreger K, Yuan H, Nicholson K, Le
P, Lyuboslavsky P, Almonte A, Murray E, Mosely C, Barber J, French A,
Balster R, Murray TF, Traynelis SF (2007) Subunit-specific mechanisms
and proton sensitivity of NMDA receptor channel block. J Physiol. 581: 107-128.
-Comment
on Dravid et al.
* Lee
CJ, Mannaioni G, Yuan H, Woo DH, Gingrich
MB, Traynelis SF (2007) Astrocytic control of synaptic NMDA receptors. J Physiol. 581: 1057-1081.
-Comment
on Lee et al.
* Traynelis
SF, Trejo J
(2007)
Protease-activated receptor signaling: new roles and regulatory
mechanisms. Curr Opin Hematol.
14: 230-235.
* Hansen
KB, Yuan
H, Traynelis SF (2007)
Structural aspects of AMPA receptor activation, desensitization and
deactivation. Curr Opin Neurobiol. 17:
281-288.
* Almonte
AG,
Hamill CE, Chhatwal JP, Wingo TS,
Barber JA, Lyuboslavsky PN, David Sweatt J, Ressler KJ, White DA,
Traynelis SF (2007) Learning and memory deficites in mice lacking
protease activated receptor-1. Neurobiol
Learn Mem. 88: 295-304.
* Hamill
CE, Caudle WM, Richardson JR, Yuan H,
Pennell KD, Greene JG, Miller GW, Traynelis SF (2007) Exacerbation of
dopaminergic terminal damage in a mouse model of Parkinson's disease by
the G-protein-coupled receptor protease-activated receptor 1. Mol Pharmacol. 72: 653-664.
* Erreger
K, Geballe MT,
Kristensen A, Chen PE,
Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen
L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF (2007)
Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and
NR2D-containing N-methyl-D-aspartate glutamate receptors. Mol Pharmacol. 72: 907-920.
* Naur
P, Hansen KB, Kristensen AS, Dravid SM,
Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis
SF, Kastrup JS (2007) Ionotropic glutamate-like receptor delta2 binds
D-serine and glycine. Proc Natl Acad
Sci U S A. 104: 14116-14121.
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2006
Publications*
* Kristensen AS, Geballe MT, Snyder JP, Traynelis SF
(2006) Glutamate receptors: variation in structure – function coupling.
Tr Pharmacol. Sci. 27: 65-69.
*
McBain CJ, Traynelis SF (2006) Malevolent
lurkers no more: NMDA receptors come of age. J Physiol. 575: 317-318.
* Paquet
M, Asay MJ, Fam SR, Inuzuka H,
Castleberry AM, Oller H, Smith Y, Yun CC, Traynelis SF, Hall RA (2006)
The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor
activity. J Biol Chem.
281:29949-29961.
* Lim LH, Wong ESP, Junge C, Ng FM, Traynelis
SF, Low C-M. (2006). Biochemical evidence for NMDA receptor NR2
subunit-specific cleavage by serine proteases. Manuscript in
preparation.
* Kristensen A, Banke TG, Schousboe A,
Traynelis SF (2006). CamKII controls coupling efficiency between
agonist binding and GluR1 subunit activation. Manuscript in
preparation.
* Kristensen A, Hansen KB, Wollmuth L, Egebjerg,
J Traynelis SF (2006) Molecular determinant of glutamate receptor
function. In “The glutamate receptors” (Swanson, Gereau), Humana, Manuscript
in press.
* Geballe MT, Erreger K, Lee CJ, Traynelis SF,
and Snyder JP (2006). Understanding agonism in the NMDA receptor:
comparing NR2A and NR2D using MD. American Chemical Society Meeting.
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2005 Publications*
*Erreger K, Traynelis SF (2005) Allosteric interaction
between zinc and glutamate binding domains on NR2A causes
desensitization of NMDA receptors. J. Physiol.
*Hamill CE, Goldshmidt A, Nicole O, McKeon RJ, Brat DJ,
Traynelis
SF (2005) Glial reactivity after damage: implications for scar
formation and neuronal recovery Clin Neurosurg. 52:29-44.
*Kristensen AS, Traynelis SF (2005) An intrusive
chaperone. Nature 435: 1042-1043.
*Erreger K, Geballe MT, Dravid SM, Snyder JP, Wyllie
DJ,
Traynelis SF (2005) Mechanism of partial agonism at NMDA
receptors for a conformationally restricted glutamate analogue. J.Neurosci.
25: 7858-7866.
*Wong E, Ng F-M, Yu C-Y, Lim P, Lim L-H, Traynelis SF,
Low C-M. (2005). Expression and characterization of soluble
amino-terminal domain of NR2B subunit of N-methyl-D-aspartate receptor.
Protein Sci. 14: 2275-2283.
* Banke TG, Dravid, SM, Traynelis SF (2005) Protons
trap NR1/NR2B NMDA receptors in a nonconducting state. J. Neurosci.
25: 42-51.
* Erreger K, Dravid SM, Banke TG, Wyllie DJ, Traynelis
SF (2005) Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B
NMDA channel
kinetics and synaptic signaling profiles. J. Physiol
563:
345-358.
* LePage KT, Ishmael JE, Low CM,
Traynelis SF, and Murray TF (2005) Differential binding properties of[3
H] dextrorphan and [ 3 H]MK-801 in heterologously expressed NMDA
receptors. Neuropharmacology 49: 1-16.
* Chen PE, Geballe MT, Stansfeld PJ, Johnston AR, Yuan
H,
Jacob AL, Synder JP, Traynelis SF, Wyllie DJ (2005). Structural
features of the glutamate binding site in recombinant NR1/NR2A
N-methyl-D-aspartate receptors determined by site-directed mutagenesis
and molecular modeling. Mol Pharmacol. 67:1470–1484.
* Nicole O, Goldshmidt A, Hamill CE, Sorensen SD, Sastre
A,
Lyuboslavsky P, Hepler JR, McKeon RJ, Traynelis SF (2005) Activation of
protease-activated receptor-1 triggers astrogliosis after brain injury.
J.Neurosci.
25(17):4319–4329.
* Fam SR, Paquet M, Castleberry AM, Oller H, Lee CJ,
Traynelis SF, Smith Y, Yun CC, Hall RA (2005) P2Y1 receptor signalling
is controlled by interaction with the PDZ scaffold NHERF-2. Proc
Natl Acad Sci U S A
102(22): 8042-8047.
* Yuan H, Erreger K, Dravid SM, Traynelis SF (2005)
Conserved structural and functional control of NMDA receptor gating by
transmembrane domain M3. J.Biol. Chem. 280: 29708-29716.
* Lee, C.J., Mannaioni, G., Junge, C.E.,
Gingrich,
M.B., and Traynelis, S.F. (2005) Potentiation of synaptic NMDA
receptors by activation of PAR1. Neuron, Manuscript under revision.
* Holm MM, Lunna M-L, Traynelis SF, Kastrup JS,
Egebjerg J (2005) Structural determinants of agonist-specific kinetics
at the ionotropic glutamate receptor 2. Proc Natl Acad Sci U S A 102:
12053-12058.
* Holm MM, Naur P, Vestergaard B, Geballe, MT, Gajhede
M, Kastrup JS, Traynelis SF, Egebjerg J (2005) A binding site tyrosine
shapes desensitization kinetics and agonist potency at GluR2: A
mutagenic, kinetic, and crystallographic study J.Biol.Chem.
280: 35469-35476.
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2004
Publications*
* Erreger,K., Chen,P., Wyllie, D.J.A, and Traynelis,
S.F. (2004) Glutamate receptor gating. CRC Critical Reviews in
Neurobiology 16: 187-224.
* Junge,C.E., Lee, C.J., Hubbard,K.B., Brat,D., Hepler,
J.R., and Traynelis, S.F. (2004). Expression of PAR1 in human brain
tissue. Experimental Neurology 188: 94-103
* Olson, E., Lyuboslavsky,P., Traynelis, S.F., McKeon,R.
(2004) PAR-1 deficiency protects against neuronal damage and
neurological deficits following unilateral cerebral hypoxia/ischemia.J.
Cereb. Blood Flow Metab. Manuscript 24: 964-971.
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2003 Publications*
* Sorensen,S.D., Nicole,O., Peavy,R.D., Montoya,L.M.,
Traynelis,S.F., and Hepler,J.R. (2003) Common signaling pathways link
activation of murine PAR1, LPA, and S1P receptors to proliferation of
astrocytes Mol.Pharmacol. 64: 1199-1209
* Junge,C.E., Sugawara,T., Mannaioni,G., Alagarsamy,S.,
Conn,P.J., Brat,D., Chan,P., and Traynelis,S.F. (2003) The contribution
of protease d receptor-1 to neuronal damage caused by transient focal
ischemia. Proc.Natl.Acad.Sci.USA 100: 13019-13024
* Jin,R., Banke,T.G., Mayer,M.L., Traynelis,S.F., and
Gouaux, E. (2003) Structural basis for partial agonist action at
ionotropic glutamate receptors. Nature Neuroscience 6: 803-810.
* ----- Nature Neuroscience News &Views
* Low,C.M., Lyuboslavsky,L., French,A., Le,P.,
Wyatte,K., Thiel,W.H., Marchan,E.M., Igarashi,K., Kashiwagi,K.,
Gernert,K., Williams,K., Traynelis,S.F. and Zheng,F. (2003) Molecular
determinants of proton sensitive NMDA receptor gating. Molecular
Pharmacology 63: 1212-1222
* ----- Mol. Pharmacol Commentary
* Poisik,O.V., Mannaioni,G., Traynelis,S.F., Smith,Y.,
and Conn,P.J. (2003) Distinct Functional Roles of the Metabotropic
Glutamate Receptors 1 and 5 in the Rat Globus Pallidus. J. Neurosci.
23: 122-130
* Banke,T.G. and Traynelis,S.F. (2003) Activation of
NR1/NR2B NMDA receptors. Nature Neuroscience 6: 144-152
*
Commentary
by (Gibb2004)
* Bowie,D., Garcia,E.P., Marshall,J., Traynelis, S.F.,
and Lange, G.D. (2003) Allosteric regulation and spatial distribution
of kainate receptors bound to ancillary proteins in HEK 293 cells. J.
Physiology 21(9): 3052-3062
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2001
Publications*
* Chesler,M., Traynelis,S.F. (2001) Proton Release as a
Modulator of Presynaptic Function. Neuron 32.6: 960-962
* Zheng,F., Erreger,K., Low,C-M., Banke,T., Lee,C.J.,
Conn,P.J., Traynelis,S.F. (2001) An allosteric interaction between the
zinc binding site and the glutamate binding site causes fast
desensitization of NR1/NR2A receptors. Nature Neurosci., 4: 894-901
* Mannaioni,G., Marino,M.J., Traynelis,S.F. and
Conn,P.J. (2001) mGluR1 and mGluR5 receptors differentially regulate
CA1 pyramidal cell function J. Neurosci. 21: 5925-5934
* Mott,D.D., Erreger,K., Banke,T.G., and Traynelis,S.F.
(2001) Open Probability of homomeric Murine 5-HT3A Serotonin Receptors
Depends on Subunit Occupancy J. Physiol. 535.2: 427-443
* Traynelis,S.F. and Lipton,S.A. (2001) Is tissue
plasminogen activator a threat to neurons? Nature Medicine 7: 17-18
* Banke,T.G.,Greenwood, J., Christensen,J.K.,
Liljefors,T., Traynelis,S.F., Schousboe,A., Pickering, D.S. (2001)
Identification of amino acid residues in glutamate receptor 1
responsible for ligand binding and desensitization. J. Neurosci. 21(9):
3052-3062
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2000 Publications*
* Banke,T.G., Bowie,D., Lee,H.-K., Huganir,R.L.,
Schousboe,A., and Traynelis,S.F. (2000) Control of GluR1 AMPA Receptor
Function by cAMP-Dependent Protein Kinase. J. Neurosci.; 20(1), 89-102.
* Gingrich,Melissa B., Junge,Candice E., Lyuboslavsky,
Polina, and Traynelis, Stephen F. (2000) Potentiation of NMDA Receptor
Function by the Serine Protease Thrombin. J. Neurosci. 20(12),
4582-4595.
* Low, C.M., Zheng,F., Lyuboslavsky,P.,
Traynelis,S.F.(2000) Molecular determinants of coordinated proton and
zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors.
Proc.Natl.Acad.Sci.USA, 97 (20), 11062-11067.
* Gingrich, M.B., Traynelis,S.F. (2000) Serine proteases
and brain damage - is there a link? Trends Neurosci. Sep;23(9):399-407.
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1998
Publications*
* Traynelis, S.F. & Jaramillo,F. (1998). Making the
most out of noise in the central nervous system. Tr. Neurosci. 21:
137-145.
* Wahl,P., Anker,C., Traynelis,S.F., Egebjerg,J.,
Rasmussen,J.S., Krogsgaard-Larsen,P., and Madsen,U. (1998). Antagonist
properties of phosphono isoxazole amino acid (ATPO) at GluR1-4 AMPA
receptor. Mol. Pharmacol. 53: 590-596.
* Traynelis,S.F., Burgess,M.F., Zheng,F.,
Lyuboslavsky,P. and Powers,J. (1998). Control of voltage independent
zinc inhibition of NMDA receptors by the NR1 subunit. J. Neurosci 18:
6163-6175.
* Zheng,F., Gingrich,M.B., Traynelis,S.F., and Conn,P.J.
(1998). Tyrosine kinase modulates Zn2+ sensitivity of NMDA receptors.
Nature Neuroscience 1: 185-191.
* Mott,D.D., Doherty,J.J., Zhang,S., Washburn,M.S.,
Fendley,M.J., Lyuboslavsky,P., Traynelis,S.F., and Dingledine,R.
(1998). Enhancement of proton inhibition: a novel mechanism of
inhibition of NMDA receptors by phenylethanolamines. Nature
Neuroscience 1: 659-667
* Traynelis, S.F. (1998). Software based correction of
single compartment series resistance errors. J.Neurosci.Meth. 86: 25-34.
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1997 Publications*
* Traynelis, S.F., and Wahl,P. (1997). Control of rat
GluR6 glutamate receptor open probability by protein kinase A and
calcineurin. J. Physiology, 503: 513-531
* Chung,D.S., Joshi,D.S., Murphy,T.J., Traynelis,S.F.,
and Conn,P.J. (1997). 4-methylhomoibotenic acid activates a novel
metabotropic glutamate receptor coupled to phosphoinositide hydrolysis.
J. Pharmacol. Exper. Therapeutics 283: 742-749.
* MacDonald, JF (1997) Phosphorylation targets the
functional gating of a glutamate channel J Physiol. 1997 Sep 15;503 (
Pt 3):469
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1986 - 1994 Publications*
* Sullivan, J.M., Traynelis, S.F., Chen, H.-S.V.,
Escobar, W., Heinemann, S.F., and Lipton, S.A. (1994). Identification
of two cysteine residues on the NMDAR1 subunit that are required for
redox modulation. Neuron 13: 929-936.
* Pulchalski, R.B., Brose, N., Louis, J.-C., Traynelis,
S.F., Egebjerg, J., Lin, F.,Kukekov, V., Wenthold, R., Rogers, S.W.,
Moran, T., Morrison, J.H., and Heinemann, S.F. (1994). Assembly of
native glutamate receptors into structurally and functionally distinct
heteromeric channels. Neuron 13: 131-147.
* Traynelis, S.F., Silver, R.A., Cull-Candy, S.G.
(1993). Estimated conductance of glutamate receptor-channels activated
during EPSCs at the cerebellar mossy fiber-granule cell synapse. Neuron
11: 279-289.
* Wyllie, D.J.A., Traynelis, S.F., and Cull-Candy, S.G.
(1993). Evidence for more than one type of non-NMDA receptor in
outside-out patches from rat cerebellar granule cells. J. Physiol. 463:
193-226.
* Miller, B., Sarantis, M., Traynelis, S.F., and
Attwell, D. (1992). Arachidonic acid potentiates NMDA channel currents.
Nature 355: 722-725.
* Silver, R.A., Traynelis, S.F., and Cull-Candy, S.G.
(1992). Rapid time-course miniature and evoked excitatory currents at
cerebellar synapses in situ. Nature 355: 163-166.
* Traynelis, S.F., and Cull-Candy, S.G. (1991).
Pharmacological properties and H+ sensitivity of excitatory amino acid
receptor channels in rat cerebellar granule neurones. J. Physiol. 433:
727-763.
* McBain, C.J., Traynelis, S.F., and Dingledine, R.
(1990). Regional variation of extracellular space in hippocampus.
Science 249: 674-677.
* Traynelis, S.F., and Cull-Candy, S.G. (1990). Proton
inhibition of N-methyl-D-aspartate receptors in cerebellar neurons.
Nature 345: 347-350.
* Kawasaki, K., Traynelis, S.F., and Dingledine, R.
(1990). Different responses of CA1 and CA3 regions to hypoxia in the
rat hippocampal slice. J. Neurophysiol. 63: 385-394.
* Traynelis, S.F., Dingledine, R., McNamara, J.O.,
Butler, L., and Rigsbee, L. (1989). Effect of kindling on
potassium-induced electrographic seizures in vitro. Neurosci. Lett.
105: 326-332.
* Traynelis, S.F. and Dingledine, R. (1989).
Modification of potassium-induced interictal bursts and electrographic
seizures by divalent cations. Neurosci. Lett. 98: 194-199.
* Traynelis, S.F. and Dingledine, R. (1989). Role of
extracellular space in hyperosmotic suppression of potassium-induced
electrographic seizures. J. Neurophysiol. 61: 927-938.
* Traynelis, S.F. and Dingledine, R. (1988).
Potassium-induced spontaneous electrographic seizures in the rat
hippocampal slice. J. Neurophysiol. 59: 259-277.
* Dingledine, R., Boland, L.M., Chamberlin,
N.L., Kawasaki, K., Kleckner, N.W., Traynelis, S.F., and Verdoorn, T.A.
(1988). Amino acid receptors and uptake systems in the mammalian
central nervous system. CRC Critical Reviews in Neurobiology 4: 1-96.
(n/a)
* Harden, T.K., Petch, L.A., Traynelis, S.F., and Waldo,
G.L. (1985). Agonist-induced alteration in the membrane form of
muscarinic cholinergic receptors. J. Biol. Chem. 260: 13060-13066.
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Traynelis Lab
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Department
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Traynelis Lab | 5062 Rollins Research Center | 1510 Clifton Drive |
Atlanta, GA 30322
Phone: 404-727-1375 Fax: 404-727-0365
Updated
07/02/08
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